Publications
2025
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Keais, G.L., Saad-Roy, C.M., Gonzalez-Sqalli, E., Powell, C.N., Rieseberg, L.H., Gawryluk, R.M.R., van den Driessche, P., Wei, K.H.-C., Loppin, B., and Perlman, S.J. (2025). A selfish supergene causes meiotic drive through both sexes in Drosophila. Proc. Natl. Acad. Sci. U. S. A. 122, e2421185122.
Huang, Y., Gao, Z.Y., Ly, K., Lin, L., Lambooij, J.-P., King, E.G., Janssen, A., Wei, K.H.-C., and Lee, Y.C.G. (2025). Polymorphic transposable elements contribute to variation in recombination landscapes. Proc. Natl. Acad. Sci. U. S. A. 122, e2427312122.
Zakerzade, R., Chang, C.-H., Chatla, K., Krishnapura, A., Appiah, S.P., Zhang, J., Unckless, R.L., Blumenstiel, J.P., Bachtrog, D., and Wei, K.H.-C. (2025). Diversification and recurrent adaptation of the synaptonemal complex in Drosophila. PLoS Genet. 21, e1011549.
2024
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Kim, B.Y., Gellert, H.R., Church, S.H., Suvorov, A., Anderson, S.S., Barmina, O., Beskid, S.G., Comeault, A.A., Crown, K.N., Diamond, S.E., et al. (2024). Single-fly genome assemblies fill major phylogenomic gaps across the Drosophilidae Tree of Life. PLoS Biol. 22, e3002697.
Betancourt, A.J., Wei, K.H.-C., Huang, Y., and Lee, Y.C.G. (2024). Causes and Consequences of Varying Transposable Element Activity: An Evolutionary Perspective. Annu. Rev. Genomics Hum. Genet. https://doi.org/10.1146/annurev-genom-120822-105708.
Wei, K.H.-C., Chatla, K., and Bachtrog, D. (2024). Single-cell RNA-seq of Drosophila miranda testis reveals the evolution and trajectory of germline sex chromosome regulation. PLoS Biol. 22, e3002605.
2023 and before
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Xu, M.-R.-X., Liao, Z.-Y., Brock, J.R., Du, K., Li, G.-Y., Chen, Z.-Q., Wang, Y.-H., Gao, Z.-N., Agarwal, G., Wei, K.H.-C., et al. (2023). Maternal dominance contributes to subgenome differentiation in allopolyploid fishes. Nat. Commun. 14, 8357.
Wang, S., Nalley, M.J., Chatla, K., Aldaimalani, R., MacPherson, A., Wei, K.H.-C., Corbett-Detig, R.B., Mai, D., and Bachtrog, D. (2022). Neo-sex chromosome evolution shapes sex-dependent asymmetrical introgression barrier. Proc. Natl. Acad. Sci. U. S. A. 119, e2119382119.
Wei, K.H.-C., Mai, D., Chatla, K., and Bachtrog, D. (2022). Dynamics and Impacts of Transposable Element Proliferation in the Drosophila nasuta Species Group Radiation. Mol. Biol. Evol. 39. https://doi.org/10.1093/molbev/msac080.
Wei, K.H.-C., Aldaimalani, R., Mai, D., Zinshteyn, D., Satyaki, P.R.V., Blumenstiel, J.P., Kelleher, E.S., and Brooks, E. (2022, June 1). Rethinking the “gypsy” retrotransposon: A roadmap for community-driven reconsideration of problematic gene names. OSF Preprints.
Wei, K.H.-C., Chan, C., and Bachtrog, D. (2021). Establishment of H3K9me3-dependent heterochromatin during embryogenesis in Drosophila miranda. Elife 10. https://doi.org/10.7554/eLife.55612.
Wei, K.H.-C., Gibilisco, L., and Bachtrog, D. (2020). Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males. Nat. Commun. 11, 5537.
Wei, K.H.-C., Mantha, A., and Bachtrog, D. (2020). The theory and applications of measuring broad-range and chromosome-wide recombination rate from allele frequency decay around a selected locus. Mol. Biol. Evol. https://doi.org/10.1093/molbev/msaa171.
Wei, K.H.-C., and Bachtrog, D. (2019). Ancestral male recombination in Drosophila albomicans produced geographically restricted neo-Y chromosome haplotypes varying in age and onset of decay. PLoS Genet. 15, e1008502.
Courret, C., Chang, C.-H., Wei, K.H.-C., Montchamp-Moreau, C., and Larracuente, A.M. (2019). Meiotic drive mechanisms: lessons from Drosophila. Proc. Biol. Sci. 286, 20191430.
Mahajan, S., Wei, K.H.-C., Nalley, M.J., Gibilisco, L., and Bachtrog, D. (2018). De novo assembly of a young Drosophila Y chromosome using single-molecule sequencing and chromatin conformation capture. PLoS Biol. 16, e2006348.
Wei, K.H.-C., Lower, S.E., Caldas, I.V., Sless, T.J.S., Barbash, D.A., and Clark, A.G. (2018). Variable Rates of Simple Satellite Gains across the Drosophila Phylogeny. Mol. Biol. Evol. 35, 925–941.
Wei, K.H.-C., Reddy, H.M., Rathnam, C., Lee, J., Lin, D., Ji, S., Mason, J.M., Clark, A.G., and Barbash, D.A. (2017). A Pooled Sequencing Approach Identifies a Candidate Meiotic Driver in Drosophila. Genetics 206, 451–465.
Wei, K.H.-C., and Barbash, D.A. (2015). Never settling down: frequent changes in sex chromosomes. PLoS Biol. 13, e1002077.
Wei, K.H.-C., Grenier, J.K., Barbash, D.A., and Clark, A.G. (2014). Correlated variation and population differentiation in satellite DNA abundance among lines of Drosophila melanogaster. Proc. Natl. Acad. Sci. U. S. A. 111, 18793–18798.
Wei, K.H.-C., Clark, A.G., and Barbash, D.A. (2014). Limited gene misregulation is exacerbated by allele-specific upregulation in lethal hybrids between Drosophila melanogaster and Drosophila simulans. Mol. Biol. Evol. 31, 1767–1778.
Satyaki, P.R.V., Cuykendall, T.N., Wei, K.H.-C., Brideau, N.J., Kwak, H., Aruna, S., Ferree, P.M., Ji, S., and Barbash, D.A. (2014). The Hmr and Lhr Hybrid Incompatibility Genes Suppress a Broad Range of Heterochromatic Repeats. PLoS Genet. 10. https://doi.org/10.1371/journal.pgen.1004240.